Buy PREDNISONE Online in Canada. Prednisone is a corticosteroid medication commonly used to treat various inflammatory and autoimmune conditions, such as asthma, arthritis, and lupus. It works by suppressing the immune system and reducing inflammation in the body. Prednisone is available in different forms, including tablets and oral solutions, and it requires careful dosage management to avoid potential side effects like weight gain, mood changes, high blood pressure, and increased infection risk. It should be used under the guidance of a healthcare provider. Prednisone oral steroid for sale.
Dosage Forms
- Tablets: 1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg, 50 mg
- Oral Solution: 5 mg/5 mL, 5 mg/mL
- Delayed-release Tablets: 1 mg, 2 mg, 5 mg
Indications
Prednisone is used to treat a variety of conditions, including but not limited to:
- Allergic reactions
- Asthma
- Autoimmune diseases like lupus and rheumatoid arthritis
- Inflammatory conditions such as inflammatory bowel disease
- Endocrine disorders like adrenal insufficiency
- Skin diseases
- Certain types of cancer
- Nephrotic syndrome
Mechanism of Action
Prednisone is a synthetic glucocorticoid, a type of corticosteroid that reduces inflammation and suppresses the immune system. It works by mimicking the effects of cortisol, a natural hormone produced by the adrenal glands, and acts on a wide range of cellular processes, influencing inflammation, metabolism, and immune responses.
Pharmacokinetics
- Absorption: Rapidly absorbed after oral administration.
- Onset of Action: Usually within 1-2 hours.
- Metabolism: Converted in the liver to its active form, prednisolone.
- Half-Life: 2 to 3 hours for prednisone, 3 to 4 hours for prednisolone.
- Excretion: Primarily excreted in the urine.
Side Effects
Before you Buy PREDNISONE Online, it’s important to consider the side effects. Common side effects of PREDNISONE may include:
- Weight gain
- Fluid retention
- High blood pressure
- Increased blood sugar levels
- Mood changes (e.g., euphoria, depression)
- Insomnia
- Gastrointestinal discomfort
- Osteoporosis (with long-term use)
- Increased risk of infection
Serious side effects can include:
- Adrenal suppression (especially with long-term use)
- Peptic ulcers
- Cataracts or glaucoma
- Severe allergic reactions
Contraindications
- Systemic fungal infections
- Hypersensitivity to prednisone or any component of the formulation
Warnings and Precautions
- Infection Risk: Prednisone suppresses the immune system, increasing the risk of infections.
- Tapering: Sudden discontinuation after long-term use can lead to adrenal insufficiency; tapering is necessary.
- Mental Health: May cause or exacerbate psychiatric conditions such as mood swings, depression, or psychosis.
- Gastrointestinal Risks: Use with caution in patients with a history of peptic ulcer disease.
Drug Interactions
- NSAIDs: Increased risk of gastrointestinal bleeding.
- Antidiabetic drugs: May reduce the effectiveness of antidiabetic agents, leading to hyperglycemia.
- Anticoagulants: Altered response to anticoagulants like warfarin, requiring close monitoring.
- Live Vaccines: Avoid administration of live vaccines during treatment due to immunosuppression.
Administration and Dosage
- Dosage: Varies depending on the condition being treated, patient’s age, weight, and response to therapy.
- Administration: Best taken with food to minimize gastrointestinal discomfort.
- Tapering: Gradual dose reduction may be necessary to prevent withdrawal symptoms, especially after long-term use.
Storage
- Store at room temperature (20-25°C or 68-77°F).
- Protect from light and moisture.
Patient Counseling Information
- Take prednisone exactly as prescribed.
- Avoid abrupt discontinuation, especially after prolonged use.
- Monitor for signs of infection.
- Inform healthcare provider of any history of ulcers, diabetes, or psychiatric conditions.
- Regular medical follow-ups are essential for monitoring side effects and adjusting dosage.
